{"id":1909,"date":"2024-10-03T08:36:46","date_gmt":"2024-10-03T05:36:46","guid":{"rendered":"https:\/\/tatd.org.tr\/arastirma\/?p=1909"},"modified":"2025-05-28T13:22:34","modified_gmt":"2025-05-28T10:22:34","slug":"txa","status":"publish","type":"post","link":"https:\/\/tatd.org.tr\/arastirma\/2024\/10\/03\/txa\/","title":{"rendered":"Traneksamik Asidin Etkinli\u011fi ve Acil Servislerde Kullan\u0131m\u0131: TATD Klinik Politika Rehberi – 2024"},"content":{"rendered":"\t\t
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TATD-AKOM Klinik Politika Rehberi: <\/h2>

Traneksamik Asidin Etkinli\u011fi ve Acil Servislerde Kullan\u0131m\u0131: TATD Klinik Politika Rehberi - 2024<\/span><\/h2>
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\n \n T\u00fcrkiye Acil T\u0131p Derne\u011fi \u2013 Ara\u015ft\u0131rma Komitesi (TATD-AKOM) taraf\u0131ndan 2024 y\u0131l\u0131nda haz\u0131rlanm\u0131\u015f ve onaylanm\u0131\u015ft\u0131r.<\/a> <\/span>\n <\/h3>\n\t\t <\/div>\n\t\t\t\t\t
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Yazar Komitesi<\/span>
<\/b><\/em>G\u00f6khan Aksel, \u015eeref Kerem \u00c7orbac\u0131o\u011flu, Mehmet Muzaffer \u0130slam, Alp \u015eener, Fatmanur Karaarslan, Merve Osaydan Sat\u0131c\u0131, Enis Ademo\u011flu, Resul \u00c7inpolat, Haldun Ako\u011flu, Faruk Dan\u0131\u015f, Fatma Sar\u0131 Do\u011fan, Emre Kudu, Murtaza Kaya, Emir \u00dcnal, Kamil Kayayurt<\/em><\/p>\n

Dan\u0131\u015fma Kurulu<\/span>
<\/em><\/strong>Ersin Aksay, Ba\u015fak Bayram, Erkan G\u00f6ksu, Mehmet Ali Karaca, Tuba Cimilli \u00d6zt\u00fcrk, Murat Ersel, Murat Pekdemir, Ay\u00e7a A\u00e7\u0131kal\u0131n<\/em><\/p><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\u00d6ZET<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Bu klinik politika rehberi, T\u00fcrkiye Acil T\u0131p Derne\u011fi (TATD) \u2013 Ara\u015ft\u0131rma Komitesi (AKOM) taraf\u0131ndan haz\u0131rlanm\u0131\u015f olup acil servis hekimlerine, acil durumlarda traneksamik asit (TXA) kullan\u0131m\u0131na dair yol g\u00f6stermeyi ama\u00e7lamaktad\u0131r.<\/p>

Antifibrinolitik bir ila\u00e7 olan TXA, plazminojeni inhibe ederek kanamay\u0131 kontrol etmek i\u00e7in kullan\u0131l\u0131r. \u00d6ncelikli olarak hemofili ve \u015fiddetli adet kanamas\u0131nda kullan\u0131lan bu ila\u00e7 zamanla travma ve cerrahiye ba\u011fl\u0131 kanamalar gibi \u00e7ok \u00e7e\u015fitli klinik senaryolarda kullan\u0131l\u0131r olmu\u015f, kullan\u0131m alan\u0131 giderek geni\u015flemi\u015ftir. Ancak, potansiyel faydalar\u0131na ra\u011fmen, TXA’n\u0131n acil durumlarda kullan\u0131m\u0131, ven\u00f6z tromboembolizm gibi ili\u015fkili riskler nedeniyle dikkatle de\u011ferlendirilmelidir. Bu klinik politika rehberi, acil servislerde kar\u015f\u0131la\u015f\u0131lan farkl\u0131 klinik senaryolarda TXA’n\u0131n endikasyonlar\u0131 ve kontrendikasyonlar\u0131 hakk\u0131nda kan\u0131ta dayal\u0131 \u00f6neriler sunmay\u0131 ama\u00e7lamaktad\u0131r. Bu rehber, ilgili klinik sorular \u00fczerine yap\u0131lm\u0131\u015f sistematik literat\u00fcr taramas\u0131 sonras\u0131nda elde edilen makalelerin \u201cGrading of Recommendations, Assessment, Development, and Evaluations\u201d (GRADE) yakla\u015f\u0131m\u0131 ile de\u011ferlendirilerek kan\u0131t ve \u00f6neri d\u00fczeylerinin olu\u015fturulmas\u0131yla ve TATD Ara\u015ft\u0131rma Komitesi’nin uzman g\u00f6r\u00fc\u015f birli\u011fi ile haz\u0131rlanm\u0131\u015ft\u0131r. \u00a0Bu belge, gastrointestinal kanama, \u00e7oklu travma, travmatik beyin yaralanmas\u0131, travmatik olmayan intrakraniyal hemoraji, hemoptizi ve burun kanamas\u0131 gibi durumlarda TXA’n\u0131n etkinli\u011fi ve g\u00fcvenli\u011fi ile ilgili \u00f6nemli klinik sorulara odaklanmaktad\u0131r. Bu sorunlar\u0131 ele alarak, bu politika rehberi, acil hekimlerinin TXA kullan\u0131m\u0131 hakk\u0131nda bilin\u00e7li kararlar almalar\u0131na yard\u0131mc\u0131 olmay\u0131 ve nihayetinde hasta bak\u0131m\u0131 kalitesini iyile\u015ftirmeyi ama\u00e7lamaktad\u0131r.<\/p>

NOT: Bu sayfada rehberinin k\u0131sa\u00a0 versiyonunu bulacaks\u0131n\u0131z. Rehberin detayl\u0131 ve tam versiyonunu a\u015fa\u011f\u0131daki “Rehberin Tamam\u0131” butonunu kullanarak indirebilirsiniz.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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G\u0130R\u0130\u015e<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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\u00a0 \u00a0 \u00a0 \u00a0 Kanama durdurma etkisi ile traneksamik asit, kimi klinik durumda hayat kurtar\u0131c\u0131 potansiyele sahipken yan etki profili sebebiyle de dikkatli kullan\u0131lmas\u0131 gereken bir ila\u00e7t\u0131r. G\u00fcncel literat\u00fcrde traneksamik asidin mortaliteyi azaltt\u0131\u011f\u0131na dair yay\u0131nlar mevcut olmakla beraber, asl\u0131nda sa\u011fkal\u0131ma faydas\u0131 olmad\u0131\u011f\u0131n\u0131 raporlayan yay\u0131nlar da mevcuttur3,4<\/sup>. Baz\u0131 yay\u0131nlarda \u00f6zellikle ven\u00f6z tromboembolik olaylarda art\u0131\u015fa neden olmas\u0131 gibi \u00f6nemli yan etkilerin raporland\u0131\u011f\u0131 d\u00fc\u015f\u00fcn\u00fcld\u00fc\u011f\u00fcnde, traneksamik asit, t\u0131pk\u0131 t\u00fcm tedaviler gibi, kar-zarar hesab\u0131n\u0131n do\u011fru bir \u015fekilde yap\u0131larak kullan\u0131lmas\u0131 gereken bir ila\u00e7t\u0131r4<\/sup>. Literat\u00fcrdeki yay\u0131nlarda raporlanan \u00e7eli\u015fkili sonu\u00e7lar, \u00e7al\u0131\u015fmalardaki metodolojik farkl\u0131lardan ve hatalardan kaynaklanabilece\u011fi gibi, farkl\u0131 klinik senaryolarda traneksamik asidin etkisinin farkl\u0131 sonu\u00e7lar veriyor olabilece\u011finden dolay\u0131 da olabilir. Bu ba\u011flamda traneksamik asidi, t\u00fcm kanama durumlar\u0131nda kullanmak yerine etkili oldu\u011fu klinik durumlar\u0131 belirleyip sadece uygun senaryolarda uygulamak daha do\u011fru bir yakla\u015f\u0131m olacakt\u0131r.<\/p>

Bu klinik politika rehberi, T\u00fcrkiye Acil T\u0131p Derne\u011fi \u2013 Ara\u015ft\u0131rma Komitesi (TATD-AKOM) taraf\u0131ndan 2024y\u0131l\u0131nda haz\u0131rlanm\u0131\u015f olup traneksamik asidin acil servislerde kullan\u0131m endikasyonlar\u0131na dair klinisyenler i\u00e7in \u00f6nemli olan klinik sorular\u0131 kan\u0131ta dayal\u0131 cevaplayarak hekimlere farkl\u0131 klinik senaryolarda traneksamik asit kullan\u0131m\u0131na dair yol g\u00f6stermeyi ama\u00e7lam\u0131\u015ft\u0131r. TATD-AKOM taraf\u0131ndan haz\u0131rlanan bu klinik politika, traneksamik asidin t\u00fcm endikasyonlar\u0131na dair bir perspektif sunmaktan ziyade ilac\u0131n acil servis kullan\u0131m alanlar\u0131na odaklanm\u0131\u015ft\u0131r.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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KR\u0130T\u0130K OLMAYAN AMA \u00d6NEML\u0130 SORULAR<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Bu rehberde s\u0131ras\u0131yla a\u015fa\u011f\u0131daki klinik senaryolardaki traneksamik asit kullan\u0131m\u0131 ile ilgili klinik sorular yan\u0131tlanacakt\u0131r;<\/p>

Senaryo 1: \u00a0<\/strong>Akut gastrointestinal (G\u0130S) kanamal\u0131 hastalar\u0131n acil servis y\u00f6netiminde traneksamik asit etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p>

Senaryo 2: \u00a0<\/strong>Kanamal\u0131 veya kanama riski y\u00fcksek multitravma hastalar\u0131nda standart tedavilere ek olarak verilen traneksamik asit etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p>

Senaryo 2A: \u00a0<\/strong>Kanamal\u0131 veya kanama riski y\u00fcksek genel multitravma hastalar\u0131nda standart tedavilere ek olarak verilen traneksamik asit etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p>

Senaryo 2B: \u00a0<\/strong>Travmatik beyin hasar\u0131 olan hastalarda standart tedavilere ek olarak verilen traneksamik asit etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p>

Senaryo 3: \u00a0<\/strong>Travma d\u0131\u015f\u0131 akut intrakranial kanamal\u0131 hastalarda standart tedaviye ek olarak kullan\u0131lan intraven\u00f6z traneksamik asit etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p>

Senaryo 3A: \u00a0<\/strong>Travma d\u0131\u015f\u0131 akut intraserebral hemorajili (\u0130SH) hastalarda standart tedaviye ek olarak kullan\u0131lan intraven\u00f6z traneksamik asit etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p>

Senaryo 3B:<\/strong>\u00a0Travma d\u0131\u015f\u0131 subaraknoid kanamal\u0131 (SAK) hastalarda standart tedaviye ek olarak kullan\u0131lan intraven\u00f6z traneksamik asit etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p>

Senaryo 4: \u00a0<\/strong>Hemoptizi hastalar\u0131nda standart tedaviye ek olarak kullan\u0131lan traneksamik asit etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p>

Senaryo 5: \u00a0<\/strong>Burun kanamal\u0131 hastalarda standart m\u00fcdahalelere alternatif olarak uygulanan lokal traneksamik asit uygulamas\u0131 etkin ve g\u00fcvenilir bir tedavi se\u00e7ene\u011fi midir?<\/p><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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METOT<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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\u00a0 \u00a0 \u00a0 Bu klinik politika rehberi haz\u0131rlan\u0131rken \u201cGrading of Recommendations, Assessment, Development, and Evaluations\u201d (GRADE)<\/a> yakla\u015f\u0131m\u0131 esas al\u0131narak ve literat\u00fcrdeki kan\u0131tlar\u0131n de\u011ferlendirilmesi ile haz\u0131rlanm\u0131\u015ft\u0131r.<\/strong> Rehberdeki \u00f6neriler haz\u0131rlan\u0131rken literat\u00fcrdeki kan\u0131tlar\u0131n seviyesi dikkate al\u0131nm\u0131\u015ft\u0131r. Kan\u0131tlar\u0131n yetersiz ya da \u00e7eli\u015fkili oldu\u011fu durumlarda ilgili klinik sorular, TATD-AKOM dan\u0131\u015fma kurulu \u00fcyeleri taraf\u0131ndan oylama yap\u0131larak \u00e7o\u011funluk karar\u0131 esas\u0131na g\u00f6re cevaplanm\u0131\u015ft\u0131r. Olu\u015fturulan bu klinik politika rehberi \u00f6ncelikle TATD ve AKOM web sitelerinde yay\u0131nland\u0131, sosyal medya \u00fczerinden duyuruldu ve TATD ile ili\u015fkili yay\u0131n organlar\u0131 taraf\u0131ndan yay\u0131nlanm\u0131\u015ft\u0131r. TATD-AKOM klinik politika rehberlerinin \u00e7ok \u00f6nemli geli\u015fmeler oldu\u011fu takdire daha erken g\u00fcncellenme opsiyonu a\u00e7\u0131k olmakla beraber rutin olarak her 3 y\u0131lda bir g\u00fcncellenmesi kararla\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r.<\/p>

K\u0131lavuzun T\u00fcrkiye Acil T\u0131p Dergisi\u2019nde yay\u0131nlanm\u0131\u015f olan \u0130ngilizce versiyonuna ula\u015fmak i\u00e7in TIKLAYIN!<\/strong><\/a><\/p>

Klinik Sorular\u0131n Belirlenmesi<\/span><\/strong><\/h5>

\u00a0 \u00a0 \u00a0 TATD-AKOM dan\u0131\u015fma kurulu taraf\u0131ndan \u00f6ncelikli olarak olu\u015fturulmas\u0131 gereken klinik politika konu ba\u015fl\u0131klar\u0131 belirlendi. Kararla\u015ft\u0131r\u0131lan konu ba\u015fl\u0131klar\u0131na dair sahadan klinik soru topland\u0131. Bu ama\u00e7la TATD ve AKOM web sitesi ve sosyal medya ara\u00e7lar\u0131 kullan\u0131larak duyurular yap\u0131ld\u0131, Google Forms kullan\u0131larak klinik sorular topland\u0131. Belirlenen s\u00fcre dahilinde (60 g\u00fcn) toplanan klinik sorular sonlan\u0131m\u0131n yan\u0131tlanma ihtiyac\u0131 \u00f6nceli\u011fine g\u00f6re 9\u2019lu Likert \u00f6l\u00e7e\u011fi kullan\u0131larak AKOM dan\u0131\u015fma kurulu \u00fcyeleri taraf\u0131ndan oyland\u0131 (1-3; kritik ve \u00f6nemli olmayan sonlan\u0131m, 4-6; kritik olmayan ama \u00f6nemli sonlan\u0131m, 7-9; kritik sonlan\u0131m)<\/strong>. Oylama sonucunda kritik olmayan ama \u00f6nemli sonlan\u0131mlar ile kritik sonlan\u0131mlar kan\u0131ta dayal\u0131 olarak cevaplanmaya uygun olarak de\u011ferlendirildi.<\/p>

\u00a0<\/h5>
Sistematik Literat\u00fcr Taramas\u0131 ve Makalelerin Belirlenmesi<\/strong><\/span><\/h5>

\u00a0 \u00a0 \u00a0 Belirlenen her klinik soru i\u00e7in SCOPUS, MEDLINE ve WOS veri tabanlar\u0131nda belirlenen anahtar kelimeler kullan\u0131larak sistematik literat\u00fcr taramas\u0131 yap\u0131lm\u0131\u015f ve ilgili klinik soruya ait k\u0131s\u0131mda payla\u015f\u0131lm\u0131\u015ft\u0131r.<\/p>

\u00a0 \u00a0 \u00a0 Her klinik soru i\u00e7in yap\u0131lan sistematik literat\u00fcr taramas\u0131nda ula\u015f\u0131lan makaleler Rayyan yaz\u0131l\u0131m\u0131na ayr\u0131 ayr\u0131 aktar\u0131ld\u0131 (6). <\/strong>Birbirine k\u00f6r iki hakem taraf\u0131ndan makalelerin ilgili klinik soruyla ili\u015fkili olup olmad\u0131klar\u0131 makalelerin \u00f6zet okumas\u0131 ile de\u011ferlendirildi. \u0130ki hakemin \u00e7eli\u015fkili karar verdi\u011fi makaleler \u00fc\u00e7\u00fcnc\u00fc bir hakem taraf\u0131ndan de\u011ferlendirildi ve nihai karar bu hakem taraf\u0131ndan verildi.<\/p>

Kan\u0131tlar\u0131n S\u0131n\u0131fland\u0131r\u0131lmas\u0131<\/span><\/strong><\/h5>

\u00a0 \u00a0 \u00a0 Her kritik soru i\u00e7in derlemeye dahil edilen makalelerin kritik okumas\u0131 en az iki ara\u015ft\u0131rmac\u0131 taraf\u0131ndan yap\u0131larak GRADEPro yaz\u0131l\u0131m\u0131 kullan\u0131larak ve GRADE yakla\u015f\u0131m\u0131na g\u00f6re kan\u0131t derecelendirilmesi yap\u0131ld\u0131 (\u00c7ok d\u00fc\u015f\u00fck, d\u00fc\u015f\u00fck, orta ve y\u00fcksek kan\u0131t d\u00fczeyi). Yanl\u0131l\u0131k (bias) risk de\u011ferlendirmesi Cochrane Rob-2 ve Robins-E ara\u00e7lar\u0131 kullan\u0131larak yap\u0131ld\u0131. Yanl\u0131l\u0131k risk de\u011ferlendirmesi birbirine k\u00f6r iki hakem taraf\u0131ndan yap\u0131ld\u0131, hakemlerin \u00e7eli\u015fkili karar verdi\u011fi makaleleri \u00fc\u00e7\u00fcnc\u00fc bir hakem de\u011ferlendirdi ve nihai karar bu hakem taraf\u0131ndan verildi.<\/p>

\u00a0 \u00a0 \u00a0 Bu klinik politika rehberi acil servislerde \u00e7al\u0131\u015fan doktorlar\u0131na y\u00f6nelik bir tavsiye metni \u00f6zelli\u011finde bir rehberdir. Hasta kapsam\u0131 ise acil servislere ba\u015fvuran eri\u015fkin hastalar olup \u00e7ocuk hastalar rehber d\u0131\u015f\u0131 b\u0131rak\u0131lm\u0131\u015ft\u0131r.\u00a0 TATD-AKOM kinik politika rehberleri, g\u00fcncel literat\u00fcrden kan\u0131ta dayal\u0131 cevaplar ve \u00f6neriler i\u00e7ermesi sebebiyle TATD-AKOM\u2019un resmi g\u00f6r\u00fc\u015f\u00fcn\u00fc yans\u0131tmaktad\u0131r. Bununla birlikte hekimler i\u00e7in kesin ve nihai \u00f6neriler de\u011fildir. TATD-AKOM, son karar\u0131 verirken hekimlerin tecr\u00fcbelerine ve hastalar\u0131n tercihlerine sayg\u0131 duyar.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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KANIT D\u00dcZEYLER\u0130NDEN \u00d6NER\u0130 D\u00dcZEYLER\u0130N\u0130N BEL\u0130RLENMES\u0130<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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GRADE yakla\u015f\u0131m\u0131 ile olu\u015fturulan kan\u0131t tablolar\u0131 esas al\u0131narak \u00f6neriler uygun \u00f6neri d\u00fczeylerine g\u00f6re geli\u015ftirilmi\u015ftir buna g\u00f6re \u00f6neri d\u00fczeyleri yanda payla\u015f\u0131ld\u0131\u011f\u0131 gibi yap\u0131lm\u0131\u015ft\u0131r;<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\u00d6NER\u0130 \u00d6ZETLER\u0130<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Rehber i\u00e7erisinde yer alan \u00f6nerilerin \u00f6zetleri yan tarafta sunulmu\u015ftur. Rehberin tamam\u0131n\u0131 tek dosyada indirmek i\u00e7in (ek dosyalar dahil) ilgili butonu t\u0131klay\u0131n!<\/p>

Rehberin tamam\u0131nda \u015funlar yer almaktad\u0131r:<\/p>

1-Klinik politika rehberinin literat\u00fcr tart\u0131\u015fmalar\u0131n\u0131n da yer ald\u0131\u011f\u0131 uzun versiyonu.
2-Ek Dosya-1. Sistematik literat\u00fcr taramada kullan\u0131lan arama sorgular\u0131 (Search Hedges).
3-Ek Dosya-2. \u00a0Sistematik literat\u00fcr taramas\u0131 ile elde edilen makalelerin ak\u0131\u015f \u015femalar\u0131.
4-Ek Dosya-3. \u00c7al\u0131\u015fmalar\u0131n \u00f6zet tablolar\u0131 (5 tablo).
5-Ek Dosya-4. \u00c7al\u0131\u015fmalar\u0131n kan\u0131t derecelendirme tablolar\u0131 (GRADE evidence level classification tables).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\u00d6NER\u0130 \u00d6ZETLER\u0130 TABLOSU<\/span><\/span><\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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TATD-AKOM Klinik Politika Rehberi: Traneksamik Asidin Etkinli\u011fi ve Acil Servislerde Kullan\u0131m\u0131: TATD Klinik Politika Rehberi – 2024 T\u00fcrkiye Acil T\u0131p Derne\u011fi \u2013…<\/p>\n","protected":false},"author":1385,"featured_media":1972,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1,10011,10018],"tags":[],"class_list":["post-1909","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","category-haber-ve-duyuru","category-klinik-politikalar"],"acf":[],"_links":{"self":[{"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/posts\/1909","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/users\/1385"}],"replies":[{"embeddable":true,"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/comments?post=1909"}],"version-history":[{"count":0,"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/posts\/1909\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/media\/1972"}],"wp:attachment":[{"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/media?parent=1909"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/categories?post=1909"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tatd.org.tr\/arastirma\/wp-json\/wp\/v2\/tags?post=1909"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}